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[Studies on chemical constituents of Cynanchum forrestii].

Yue Liu, Jing Liu, Shi‐Shan Yu, Xiang‐Zhong Huang, You-Cai Hu

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Abstract

OBJECTIVE: To study the chemical constituents of Cynanchum forrestii. METHOD: Chromatographic techniques were applied to isolated chemical constituents. The structures were identified on the basis of physico-chemical constants and spectroscopic data. RESULT: Eight compounds were isolated from the 95% ethanol extract of the roots of C. forrestii and elucidated as ( + ) -5'-methoxyisolariciresinol 3a-O-beta-D-glucopyranoside (1), hexahydroxycholest-7-en-6-one (2), tylophorinidine (3), sucrose (4), palmitic acid (5), beta-sitosterol (6), daucosterol (7), nonanedioic acid (8). CONCLUSION: Compounds 1-3 from this genus, and compounds 4-8 from the plant were obtained for the first time.

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What this paper is about

OBJECTIVE: To study the chemical constituents of Cynanchum forrestii. METHOD: Chromatographic techniques were applied to isolated chemical constituents. The structures were identified on the basis of physico-chemical constants and spectroscopic data. RESULT: Eight compounds were isolated from the 95% ethanol extract of the roots of C. forrestii and elucidated as ( + ) -5'-methoxyisolariciresinol 3a-O-beta-D-glucopyranoside (1), hexahydroxycholest-7-en-6-one (2), tylophorinidine (3), sucrose (4), palmitic acid (5), beta-sitosterol (6), daucosterol (7), nonanedioic acid (8). CONCLUSION: Compounds 1-3 from this genus, and compounds 4-8 from the plant were obtained for the first time.

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Available abstract

OBJECTIVE: To study the chemical constituents of Cynanchum forrestii. METHOD: Chromatographic techniques were applied to isolated chemical constituents. The structures were identified on the basis of physico-chemical constants and spectroscopic data. RESULT: Eight compounds were isolated from the 95% ethanol extract of the roots of C. forrestii and elucidated as ( + ) -5'-methoxyisolariciresinol 3a-O-beta-D-glucopyranoside (1), hexahydroxycholest-7-en-6-one (2), tylophorinidine (3), sucrose (4), palmitic acid (5), beta-sitosterol (6), daucosterol (7), nonanedioic acid (8). CONCLUSION: Compounds 1-3 from this genus, and compounds 4-8 from the plant were obtained for the first time.

Key concepts: Daucosterol, Chemical constituents, Palmitic acid, Chemistry, Chromatography, Organic chemistry, Fatty acid

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