Optimization of the Extraction Technology for Water Soluble Components in Wusan Granules with an Orthogonal Test

Objective:To optimize the extraction technology for water soluble components in wusan granules. Methods:An orthogonal test with the use of an L 9(3)4 orthogonal table was adopted for the optimization. Recovery rate of the dry extract and the content of emodin served as the indices. The 4 factors influencing the decoction extraction of water soluble components of the drug--time of soaking of the drug, amount of water added, time of decoction and times of decoction were kept under observation. Results:The optimized extraction technology was as follows: 10 volumes of water were added to 1 volume of the crude drug, the drug was soaked for 60 min and decocted for 3 times, each decoction lasting 60 min. Conclusion:The method was shown to be suitable for the decoction extraction of water soluble componeuts in wusan granules.