2015•China Modern DoctorRequires access

Clinical analysis about 66 cases of the triple-negative breast cancer

Zhong Juhu

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Abstract

Objective To study the clinical characteristics of triple-negative breast neoplasms patients, and analyze the factors affecting its prognosis. Methods Use medical record survey method,collect the hospital from September2011 to October 2013 of 66 cases of three negative breast cancer,it can be divided into triple-negative breast(TNBC groups,16 cases) and the non-triple-negative breast group(non-TNBC group,50 cases). With χ2test and Fisher exact probability for the survival of patients situation and clinical pathology characteristic clinical data as well as to the age,tumor size,axillary lymph node number, pathological type,factors such as local and distant metastasis for statistical analysis. Results The triple-negative breast cancer group and the non-triple-negative breast cancer in clinical pathology characteristics, menstrual status differences had no statistical significance(P0.05); pathologic examination, tumor size, axillary lymph node number, pathological type, such as local and distant metastasis showed in the two groups was statistically difference(P0.05); the recurrence metastasis rate of two groups had a differences with statistically significant(P0.05). Conclusion The triple-negative was a high risk of breast cancer, breast cancer in premenopausal women. The association between tumor size and axillary lymph node status was not big; tumor diameter of the head,high recurrence rate, distant metastasis occurred early; should promote targeted drugs appeared for triple-negative breast cancer patients.

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Objective To study the clinical characteristics of triple-negative breast neoplasms patients, and analyze the factors affecting its prognosis. Methods Use medical record survey method,collect the hospital from September2011 to October 2013 of 66 cases of three negative breast cancer,it can be divided into triple-negative breast(TNBC groups,16 cases) and the non-triple-negative breast group(non-TNBC group,50 cases). With χ2test and Fisher exact probability for the survival of patients situation and clinical pathology characteristic clinical data as well as to the age,tumor size,axillary lymph node number, pathological type,factors such as local and distant metastasis for statistical analysis. Results The triple-negative breast cancer group and the non-triple-negative breast cancer in clinical pathology characteristics, menstrual status differences had no statistical significance(P0.05); pathologic examination, tumor size, axillary lymph node number, pathological type, such as local and distant metastasis showed in the two groups was statistically difference(P0.05); the recurrence metastasis rate of two groups had a differences with statistically significant(P0.05). Conclusion The triple-negative was a high risk of breast cancer, breast cancer in premenopausal women. The association between tumor size and axillary lymph node status was not big; tumor diameter of the head,high recurrence rate, distant metastasis occurred early; should promote targeted drugs appeared for triple-negative breast cancer patients.

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Available abstract

Objective To study the clinical characteristics of triple-negative breast neoplasms patients, and analyze the factors affecting its prognosis. Methods Use medical record survey method,collect the hospital from September2011 to October 2013 of 66 cases of three negative breast cancer,it can be divided into triple-negative breast(TNBC groups,16 cases) and the non-triple-negative breast group(non-TNBC group,50 cases). With χ2test and Fisher exact probability for the survival of patients situation and clinical pathology characteristic clinical data as well as to the age,tumor size,axillary lymph node number, pathological type,factors such as local and distant metastasis for statistical analysis. Results The triple-negative breast cancer group and the non-triple-negative breast cancer in clinical pathology characteristics, menstrual status differences had no statistical significance(P0.05); pathologic examination, tumor size, axillary lymph node number, pathological type, such as local and distant metastasis showed in the two groups was statistically difference(P0.05); the recurrence metastasis rate of two groups had a differences with statistically significant(P0.05). Conclusion The triple-negative was a high risk of breast cancer, breast cancer in premenopausal women. The association between tumor size and axillary lymph node status was not big; tumor diameter of the head,high recurrence rate, distant metastasis occurred early; should promote targeted drugs appeared for triple-negative breast cancer patients.

Key concepts: Medicine, Breast cancer, Triple-negative breast cancer, Pathological, Oncology, Internal medicine, Clinical significance, Cancer

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