Comparison of the Application Value of Mini-mental State Examination and Montreal Cognitive Assessment in Lacunar Infarction Patients with Cognitive Impairment

Objective To compare the application value of mini-mental state examination(MMSE) and Montreal cognitive assessment(MoCA) in detecting cognitive impairment in lacunar infarction(LI) patients.Methods The LI patients were first screened by MMSE,and those having a normal education-adjusted score were further assessed by MoCA(26 as the cut-off score).The patients with MoCA score less than 26 were selected into cognitive impaired LI-CI group and the patients with more than 26 were classified as normal control LI-NC group.Fifty healthy individuals were recruited in the healthy control group(NC group).The total score and the score of each cognitive field of MoCA among three groups was compared and analyzed.Results 53%(50/94) LI patients with normal MMSE had MoCA 26.There was a statistical significant difference(P 0.01) of the cognitive function between these cases and patients with MoCA ≥ 26.The MoCA score of LI-CI group was less than LI-NC group in visuospatial,executive,naming,delayed recall,abstraction and so on.The differences were statistical significant(P 0.05).Conclusion The cognitive impairment of those patients with normal MMSE score but abnormal MoCA score were mainly in visuospatial,executive,naming,delayed recall,abstraction and so on.MoCA is more sensitive than MMSE in cognitive impairment screening in LI patients.