2012Zhongguo quanke yixueRequires access

Application Value of Montreal Cognitive Assessment in Lacunar Infarction Patients with Cognitive Impairment

Yanxing Zhang

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Abstract

Objective To analyze the application value of Montreal Cognitive Assessment(MoCA)(Chinese version) in detecting cognitive impairment in patients with lacunar infarction(LI).Methods The patients confirmed with LI were first screened by Mini-Mental State Examination(MMSE),and patients having normal MMSE score were further assessed by MoCA after education adjustment(26 as the cut-off score).The patients with MoCA score less than 26 were selected as cognitive impaired LI-CI group and the patients with more than 26 were selected as normal control LI-NC group.MoCA score,MMSE score and scores of each cognitive field of MoCA were compared between the two groups.Results 53%(50/94) LI patients with normal MMSE score had MoCA socre26,and these patients′ cognitive function showed statistically significant difference with the patients who had MoCA socre≥26(P0.01).The scores of visuospatial and executive function,naming,Abstract and delayed recall of the LI-CI group showed statistically significant differences with those of the LI-NC group(P0.05).Conclusion MoCA is more sensitive than MMSE in screening cognitive impairment in LI patients.The cognitive impairments of patients with normal MMSE but abnormal MoCA are mainly visuospatial and executive function,naming,delayed recall,Abstract and so on.

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What this paper is about

Objective To analyze the application value of Montreal Cognitive Assessment(MoCA)(Chinese version) in detecting cognitive impairment in patients with lacunar infarction(LI).Methods The patients confirmed with LI were first screened by Mini-Mental State Examination(MMSE),and patients having normal MMSE score were further assessed by MoCA after education adjustment(26 as the cut-off score).The patients with MoCA score less than 26 were selected as cognitive impaired LI-CI group and the patients with more than 26 were selected as normal control LI-NC group.MoCA score,MMSE score and scores of each cognitive field of MoCA were compared between the two groups.Results 53%(50/94) LI patients with normal MMSE score had MoCA socre26,and these patients′ cognitive function showed statistically significant difference with the patients who had MoCA socre≥26(P0.01).The scores of visuospatial and executive function,naming,Abstract and delayed recall of the LI-CI group showed statistically significant differences with those of the LI-NC group(P0.05).Conclusion MoCA is more sensitive than MMSE in screening cognitive impairment in LI patients.The cognitive impairments of patients with normal MMSE but abnormal MoCA are mainly visuospatial and executive function,naming,delayed recall,Abstract and so on.

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Available abstract

Objective To analyze the application value of Montreal Cognitive Assessment(MoCA)(Chinese version) in detecting cognitive impairment in patients with lacunar infarction(LI).Methods The patients confirmed with LI were first screened by Mini-Mental State Examination(MMSE),and patients having normal MMSE score were further assessed by MoCA after education adjustment(26 as the cut-off score).The patients with MoCA score less than 26 were selected as cognitive impaired LI-CI group and the patients with more than 26 were selected as normal control LI-NC group.MoCA score,MMSE score and scores of each cognitive field of MoCA were compared between the two groups.Results 53%(50/94) LI patients with normal MMSE score had MoCA socre26,and these patients′ cognitive function showed statistically significant difference with the patients who had MoCA socre≥26(P0.01).The scores of visuospatial and executive function,naming,Abstract and delayed recall of the LI-CI group showed statistically significant differences with those of the LI-NC group(P0.05).Conclusion MoCA is more sensitive than MMSE in screening cognitive impairment in LI patients.The cognitive impairments of patients with normal MMSE but abnormal MoCA are mainly visuospatial and executive function,naming,delayed recall,Abstract and so on.

Key concepts: Montreal Cognitive Assessment, Medicine, Cognition, Cognitive impairment, Internal medicine, Recall, Audiology, Psychiatry

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