Change of Serum 25-hydroxyvitamin D_3 Level in Elderly with Metabolic Syndrome and Its Clinical Significance

Objective To explore the relationship between serum 25(OH) D3level and metabolic syndrome(MS) in elderly.Methods Blood pressure(BP),height,weight were measured,body mass index(BMI) calculated,fasting blood glucose(FBG),lipids,glycated hemoglobin(HbA1c) etc.determined in 167 MS patients and 187 controls aged over 60 years,from September 2010 to October 2012 in People's Hospital of Peking University.Enzyme-linked immunosorbent assay was used to detect 25(OH) D3level.The difference in the above indicators between 2 groups and the correlation of 25(OH) D3with these indicators were analyzed comparatively.Results Serum 25(OH) D3level was lower in MS group than in control group 〔(29.9 ± 6.6) nmol / L,(32.7 ± 7.1) nmol / L,P 0.05〕,there was significant difference in grading of 25(OH) D3level(P 0.05).Pearson correlation analysis showed that serum 25(OH) D3was negatively correlated with BMI,triglycerides,FBG and HbA1c(r =-0.116,-0.110,-0.118,-0.143,P 0.05).Conclusion Serum 25(OH) D3level,low in elderly MS patients,is correlated with BMI,lipids,blood glucose and other indicators.