Effect of amiodarone for atrial fibrillation in patients with acute myocardial infarction

Objective:To evaluate the efficacy and safety of intravenous amiodarone for atrial fibrillation with acute myocardial infarction.Method:Thirty-four patients with acute myocardial infarction and atrial fibrillation were treated with amiodarone.The first bolus of amiodarone was given at 150 mg intravenous followed by 0.5-1 mg/min in fusion.The effect was defined as returning to sinus rhythm in 24 hour.Result:Sixteen patients were revevted to sinus rhythm(47.1%)within 2 hour,24 patients were reverted to sinus rhythm(70.6%)within 24 hour,29 patients were revevted to sinus rhythm(85.3%),within 48 hour.side effects were observed in 5 patients(14.7%).Conclusion:Amiodarone is effective and safe for treatment of atrial fibrillation with acute myocardial infarction.