Clinical analysis of three kinds of syphilis serological test methods

Objective To explore common three syphilis serologic test methods,so to select the most appropriate screening method of syphilis. Methods The syphilis serological screening of the clinic patients was conducted lay means of most commonly rapid plasma reagin (RPR),syphilis antibody specificity enzyme-linked immunosorbent test (TP-ELISA) and Treponema pallidum particle agglutination (TPPA) three methods for hospital,which are very popular in the clinical laboratory for syphilis test. Results By the three kinds of test methods,there was no significant differences in TP-ELISA and TPPA method detection result compared with the one of RPR is of great significant difference (P 0.01). Conclusion The laboratory shall reasonably select three different methods for syphilis,which will help to reduce the misdiagnosis rate of syphilis,and provide a reference basis for the identification of the development of syphilis in clinic,moreover,it is of great significance in the judgement of syphilis installment,healing and drug efficacy.