Timing of Postoperative Hyperbaric Oxygen Therapy in Patients with Hypertensive Intracerebral Haemorrhage and Its Impact on Complicated Stress Ulcer Bleeding

Objective To discuss the correlations between postoperative hyperbaric oxygen therapy for hypertensive basal ganglia intracerebral haemorrhage and complicated stress ulcer bleeding and to explore the impact of treatment timing on prognosis.Methods A total of 586 postoperative patients with hypertensive basal ganglia intracerebral haemorrhage were randomly assigned to group A(control group),group B(hyperbaric oxygen therapy was carried out 7~14 days after operation),and group C(hyperbaric oxygen therapy was carried out 15~30 days after operation).Incidence rates of stress ulcer bleeding and ADL scores were compared among the three groups after 6 months of follow-up.Results Incidence rates of stress ulcer bleeding remained comparable among the three groups 0~6 days after operation(P0.05),became significantly different in group B compared with group A and C 7~14 days after operation(P0.01),and became significantly different between group A and C 15~30 days after operation(P0.01).ADL scores after 6 months of follow-up were(45.7±28.8)score,(78.7±22.8) score,and(62.8±28.9) score among group A,group B and group C respectively(F=52.885,P0.05).Significant differences between group B and group A,group B and group C,group C and group A on prognosis were also noted(q=-33.008,P0.01;q=15.893,P0.01;q=17.115,P0.01).Grade distribution based on.ADL scores showed significant differences among the three groups(H=69.064,P0.05).Conclusion Hyperbaric oxygen therapy exhibits notable curative effects for postoperative hypertensive basal ganglia intracerebral haemorrhage and 7~14 days after operation is the best timing for such therapy.Despite the increased stress ulcer bleeding rate,it is still worth recommendation for the decreased rate of disability.