Comparison of transfusion of cryopreserved platelet and liquid preserved platelet in CABG

Objective To compare the hemostatic effect of cryopreserved platelet and liquid preserved platelet in patients undergoing cardiopulmonary artery bypass grafting (CABG). Methods Sixty in-patients were designed into two groups(groups 1and 2, each n=30 ), according to identical sex, similar age (±1 year)and the same state of illness in cardiopulmonary artery. Patients in group 1 received transfusion of leucocyte reduction red blood cell(LR-RBC) and cryopreserved platelet(CP), while patients in group 2 received transfusion of LR-RBC andliquid preserved platelet(LPP). The hemostatic effect was evaluated by the average blood transfusion amount, and the amount of ooze fluid in 24 h after operation. Results The average blood transfusion amount was 613.33 ml(composed of 309.15 ml LR-RBC and 304.18 ml CP) and 751.67 ml(composed of 436.50 ml LR-RBC and 314.17 ml LPP) in groups 1 and 2 respectively. Two groups were compared. There was significant difference between both. The average amount of ooze fluid in 24 h after operation in groups 1 and 2 was 388 ml and 454 ml respectively. Conclusion Cryopreserved platelet is superior to liquid preserved platelet in reducing blood loss and need for homologous blood product transfusion inCABG, suggesting that cryopreserved platelet has better hemostatic effect thanliquid preserved platelet.