Prevention of new occurred atrial fibrillation in coronary heart disease patients by Simvastatin

Objective: To evaluate the effect of Simvastatin on prevention of new occurred atrial fibrillation(AF) in coronary heart disease patients.Methods: 322 patients with coronary heart disease(CHD) were randomly divided into two groups,Simvastatin group(164 cases) was given Simvastatin 10 mg and the control group(158 cases) was given routine treatment,changes of levels of high sensitive C-reactive protein in two groups were observed before and after treatment.The incidence rates of AF were measured in following-up.Results: The level of hs-CRP decreased after treatment in two groups,Simvastatin group decreased more obvious(P0.05).54 cases of the 322 patients developed AF during follow-up,8 case(4.9%) in the Simvastatin group and 46 cases(29%) in the control group,the incidence of AF in the Simvastatin group was significantly less than the control group(P0.05).Conclusion: Simvastatin can reduce the incidence of AF obviously in coronary heart disease patients.