Protection of Kidney-Enrichment And Blood-Quickening Decoction on Vasculopathy and Kidney in Type 2 Diabetic Rats.
Liangliang Du
Abstract
Liangliang Du
Abstract
Objective: To explore the effect of Kidney-Enrichment And Blood-Quickening Decoction on blood sugar,fast ing insulin,blood fat,renal function,and the vasculitis index of ET,NO,INS and TNF-α.Methods: 42 female Wister rats were divided into model control group,Chinese medicine group,melbine group,Chinese medicine-melbine group and blank control group.After intragastric administration of 8 weeks,the biochemical indicator,vasculitis index and renal function were tested.Results: Kidney-Enrichment And Blood-Quickening Decoction can reduce the serum NO,INS,TNF-α,TG,BUN,CREA and UA in Type 2 diabetic rats.Conclusion: Kidney-Enrichment And Blood-Quickening Decoction can relieve the vas cular inflammation,with protective function on kidney.And the function was more obvious with low dosage of melbine in ear ly stage.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective: To explore the effect of Kidney-Enrichment And Blood-Quickening Decoction on blood sugar,fast ing insulin,blood fat,renal function,and the vasculitis index of ET,NO,INS and TNF-α.Methods: 42 female Wister rats were divided into model control group,Chinese medicine group,melbine group,Chinese medicine-melbine group and blank control group.After intragastric administration of 8 weeks,the biochemical indicator,vasculitis index and renal function were tested.Results: Kidney-Enrichment And Blood-Quickening Decoction can reduce the serum NO,INS,TNF-α,TG,BUN,CREA and UA in Type 2 diabetic rats.Conclusion: Kidney-Enrichment And Blood-Quickening Decoction can relieve the vas cular inflammation,with protective function on kidney.And the function was more obvious with low dosage of melbine in ear ly stage.
Key concepts: Decoction, Medicine, Kidney, Blood stasis, Internal medicine, Traditional Chinese medicine, Renal function, Endocrinology