2002•Yati yasui yazhoubingxue zazhiRequires access
Experimental study of root canal medication with calcium hydroxide in animal
WU Hai-zhen
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Abstract
AIM:To compare the drug closing effect of calcium hydroxide or FC in pulpectomy and root canal therapy in rat. METHODS: The root canals of first mandibular molar teeth of Wistar rats were used to establish the animal model of apicitis. The root canals were treated with pulpectomy and root canal therapy and closed by calcium hydroxide or FC. Histopathology in periapical region was surveyed for 1、2、3、 6 and 10 weeks after operation respectively. RESULTS: Concerning the group of the pulpectomy, there was early inflammation in FC group while there was gentle inflammation in the calcium hydroxide group. There was new periapical osteoanagenesis in the group of calcium hydroxide after 10 weeks. Concerning the root canal therapy group, the inflammation disappeared faster in the FC group than that in the calcium hydroxide group. The inflammation disappeared completely all after 3 weeks.There was new periapical osteoanagenesis in the calcium hydroxide group after 10 weeks. CONELUSION: Calcium hydroxide has considerable drug closing effect on rat pulpectomy and root canal therapy.