The results of nasopharyngeal carcinoma treated by ~( 60) Co external irradiation plus intracavitary radiotherapy using the high dlose rate afterloading technique

Objective: The long term results and radiation sequelae of nasopharyngeal carcinoma treated by 60 Co external irradiation plus the high dose rate afterloading intracavity radiation (AIR) were analysed.Methods: From July 1985 to August 1988,58 patients with nasopharyngeal carcinoma were treated by 60 Co external irradiation plus the high dose rate AIR.The AIR was given as a routine boost or for residual disease.The external irradiation dose varied from 55 to 70 Gy,whereas AIR dose ranged from 10 to 45 Gy.Results: All patients were followed up for more than 5 years.The 5 year local control rate was 84.5%.The 5 year actuarial survival and disease free rates were 75.9%,65.5% respectively.Conclusion: We think that AIR for nasopharyngeal carcinoma is indicated for boosting the dose to the nasopharyngeal cavity with appropriated reduction in external irradiation dose,and for residual disease after primary external radiotherapy.