Clinical Observation of Carvedilol on Heart Failure Induced by Hypertensive Heart Disease

Objective To evaluate the efficacy and safety of carvedilol in patients with chronic heart failure.Methods 72 cases with heart failure induced by hypertensive heart disease were randomly divided to a treatment group with carvidilol and a control group with basic treatment.Before and after therapy the indexes such as heart rate,blood pressure,left ventricular function and pathogenetic condition change were compared.Results The ejection fraction increased in the two groups,the left ventricular end diastolic volume and the ventricular end-systolic volume decreased at the end of the experiment,but the change of ejection fraction,the left ventricular end diastolic volume and the ventricular end-systolic volume in treatment group were better than those in control group.Conclusion It is safe and effective to treat heart failure induced by hypertensive heart disease with carvedilol on the basis of controlling blood pressure and hear failure.