Clinical evaluation of the therapeutic efficacy of biventricular pacing in patients with congestive heart failure

AIM: To evaluate the clinical and hymodynomic efficacy of biventricular pacing in the treatment of patients with chronic congestive heart failure. METHODS:11 patients with congestive heart failure and intraventricular conduction delay, ejection fraction 35% were recruited for biventricular pacing therapy. The hemodynamic parameters with biventricular pacing were evaluated by the echocardiography and Swan-Gans catheterization before and after the operation. RESULTS: After the biventricular pacing, the clinical symptoms were improved and cardiac output, cardiac index and LV ejection fraction increased. The wedged pressure of pulmonary capillaries went down;the size of mitral regurgitation was reduced and the left ventricular end-diastolic diameter decreased(75±8 vs 68±6 mm, P 0.05) after 3 months' pacing. CONCLUSION: The biventricular pacing reverses left ventricular remodeling and improves the clinical symptoms, cardiac function in patients with congestive heart failure and intraventricular conduction delay.