Study of pathogens detected from blood culture samples and its drug resistance

Objective To investigate the distribution of pathogens and drug resistance in blood infection samples.Methods BACTEC9120 automated blood culture system and its corresponding adult aerobic resin bottles and bottles containing hemolysin anaerobic,aerobic resin flask children were used.All pathogens were identified in accordance with routine operating procedures.Drug sensitivity test was performed by K-B diffusion method and the results were analysed by WHONET 5.5 software.Results Totally 109 strains of 28 species pathogens were isolated from 1 290 blood culture samples,with the positive rate of 8.4%.Gram-positive cocci drugs tested were varied,but there were no vancomycin resistant strains found.Gram-negative bacilli was resistant to majority of drug tested but no imipenem(IPM) and meropenem(MEM)resistant strains were found.Conclusion Wide spectrum of pathogen is found in blood culture,and the primary pathogen is Gram-positive cocci,followed by gram-negativ bacilli.Drug resistance is prevalent,blood culture and drug resistance should be carried out in time to guide rational use of antibiotics.