Synthesis of 3-chloro-2-butanone by oxidation-chlorination in situ

3-chloro-2-butanone was synthesized by chlorination in situ with HC1-H2O2. The influences of reaction conditions such as mole ratio, reaction time, reaction temperature and some metal salts were examined in detail. The optimum preparation conditions were CuCl2 as catalyst, n(butanone):n(HCl):n(H2O2)=2:l:1.3, reaction temperature 78℃ and reaction time is 5h. the conversion of butanone amount to 52.43%, the selectivity of 3-chloro-2-butanone is over 76% and its purity is over 98%.