A Study On Synthesis of 2-Chloro-Phenyl-Thiourea

2-Chloro-phenyl-thiourea was prepared from o-chloro-aniline and ammonium thiocyanate with water solution.The effect of the proportion of raw materials,the reaction temperature and the reaction time were investigated.The optimum reaction conditions were determined,i.e.,n(o-chloro-aniline):n(ammonium thiocyanate)=1:1.05,n(o-chloro-aniline):n(hydrochloric)=1:1.1,reaction temperature 80℃and reaction time 16 h. The yield and purity of the product reached 90.0% and 93.9% respectively with the optimal process.