Application of Gas Chromatography/Mass SpectrometrySelected Ion Monitor Technique for the Simultaneous Determination of 21 Kinds of Phthalates in Leather Products

In this paper,a GS/MS-SIM analysis method was established for the simultaneous determination of 21 kinds of phthalates in leather products.Phthalates in leather products were ultrasonically extracted at 40℃ using hexane as the extraction solvent,then the extracts were treated,followed by the analysis applying gas chromatography/mass spectrometry-selected ion monitor(GC/MS-SIM) technique.The proposed method was accurate,rapid and sensitive.The detection limits of DINP and DIDP were 1.0 mg/kg and 2.0 mg/kg,respectively.The detection limits of other phthalates were all less than 0.4mg/kg.The spiked average recoveries changed from 89.99% to 98.40%.The relative standard deviation(RSD) of precision experiment was all less than 10%.The proposed method was applied successfully to the determination of phthalates in 47 kinds of commercially available leather products and phthalates were found to exist in two samples.