Preparation of Schisandra chinensis wine and effect on sleep improvement

The Schisandra chinensis wine's main materials were Schisandra chinensis,ginseng and wine,which was prepared by extracting,filtering,blending,filtering,and filling.The main qualifications were detected according to national standard,and its effect on improving sleep was carried out by the experiments of direct sleep test,Sodium Pentobarbital induced prolonging sleeping time test,the sleepproducing test of Sodium Pentobarbital sub-threshold dosage and incubation period test of Sodium Pentobarbital.The results showed that:After 30 days of administrated orally of the wine to Kunming mice,no significant difference(P0.05) of body weight was found between each dose group with the control group.And the direct sleeping effect of the test material was not observed.There was significant difference(P0.05) between 50.0 mL/kg.bw dosage of the sample with the blank and wine-based control group,respectively,which could significantly extend the sleeping time of tested mice induced by Sodium Pentobarbital,significantly shorten incubation period induced by Sodium Pentobarbital.However,no significant effect was observed to the sleeping-induced sleep-producing test of Sodium Pentobarbital sub-threshold dosage.Conclusion:Schisandra chinensis wine could improve sleep.