Studies on the chemical constituents in leaves of Rosa Laevigata Michx

Objective To investigate the chemical constituents from leaves of Rosa Laevigata Michx.Methods The chemical constituents were isolated and purificated by silica gel column chromatography,Sephadex LH-20 and semi-preparative RP-HPLC.Their structures were identified by spectral data together with physicochemical analysis.Results Twelve known compounds were isolated and identified as catechin(1),quercetin(2),naringenin(3),kaempferol(4),ethyl gallate(5),p-hydroxyl ethyl cinnamate(6),ω-hydroxypropioquaiacone(7),hydroxytyrosol(8),o-hydroxybenzoic acid(9),scopoletin(10),ethyl α-D-arabinofuranoside(11),methyl β-D-glucopyranoside(12).Conclusion Compound 11 was isolated from genus Rosa for the first time,compounds 3,5~9 were isolated from leaves of Rosa Laevigata Michx for the first time.