Distribution and Drug Resistance of Clinical Pseudomonas Aeruginosa Isolates

Ojbective To investigate the distribution and drug resistance of clinical Pseudomonas aeruginosa isolates.Methods A statistic analysis for the specimen source,departments with infection and drug resistance condition to 250 isolates was conducted inretrospective manner.Results Among 250 strains 241(96.4%)come from sputum,the proportion of these strains from ICU was 65.2%,from neurology department was 18.4% mainly.The result of drug susceptibility showed that P.aeruginosa had a high resistance rate to the chloramphenicol,minocycline,gentamicin,piperacillin,cefotaxime,ceftriaxome and sulfonamides antibiotics,respectively,accounted for more than 70%,and had a lower resistance rate to carbapenem,amikacin,ceftazidime,the lowest was to imipenem(20%),and to amikacin(24.8%).Conclusion Clinical isolates of P.aeruginosa come from the sputum and ICU mainly,but their resistant rates are rather high and multi-drug resistant.We should pay more attention to the surveillance of antimicrobial resistance of P.aeruginosa in clinics.