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2006•Journal of Northwest Normal UniversityRequires access

The research progress of RNA interference

Guoan Liu

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Abstract

RNA interference(RNAi) is the sequence-specific gene silencing induced by double-stranded RNA(dsRNA).It becomes research hotspot at present.It has been applied in some aspects and will be used widely in the future.Molecular mechanisms,biological functions and research strategies of RNAi are reviewed.The applications of RNAi in gene function,gene therapy and plant quality betterment are also reviewed.

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What this paper is about

RNA interference(RNAi) is the sequence-specific gene silencing induced by double-stranded RNA(dsRNA).It becomes research hotspot at present.It has been applied in some aspects and will be used widely in the future.Molecular mechanisms,biological functions and research strategies of RNAi are reviewed.The applications of RNAi in gene function,gene therapy and plant quality betterment are also reviewed.

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Available abstract

RNA interference(RNAi) is the sequence-specific gene silencing induced by double-stranded RNA(dsRNA).It becomes research hotspot at present.It has been applied in some aspects and will be used widely in the future.Molecular mechanisms,biological functions and research strategies of RNAi are reviewed.The applications of RNAi in gene function,gene therapy and plant quality betterment are also reviewed.

Key concepts: RNA interference, RNA silencing, Computational biology, Biology, RNA, Gene silencing, Gene, RNA-induced silencing complex

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