Clinical Observation of Modified Huanglian Ejiao Decoction in the Treatment of Elderly Hypertensive Patients with Insomnia

OBJECTIVE:To observe clinical efficacy of modified Huanglian ejiao decoction in the treatment of elderly hypertensive patients with insomnia. METHODS:120 elderly hypertensive patients with insomnia of disharmony between heart and kid- ney were randomly divided into control group and experimental group. On the basis of conventional antihypertensive treatment,the experimental group took modified Huanglian ejiao decoction 300 ml/time twice a day;control group was given Naoliqing pills 10 pills/time twice a day. A treatment course lasted for 28 days. Result of pittsburgh sleep quality(PSQI),ambulatory blood pressure and symptoms improvement were recorded before and after medication. RESULTS:Total score of PSQI,sleep quality,sleep efficacy,hours of sleep,dyssomnia and sleep latency were all lower in experimental group than in control group significantly(P0.05);there was no significant difference in ambulatory blood pressure(P0.05);the improvement of soreness and weakness of waist and knees,dry and red tongue,hot flash and night sweat were improved significantly,and total score of disharmony between heart and kidney were decreased significantly(P0.05). CONCLUSIONS:Modified Huanglian ejiao decoction improves sleep quali- ty of elderly hypertensive patients with disharmony between heart and kidney and keeps stable blood pressure,which provide reliable reference for clinical treatment.