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Studies on Bacteriostasis of Canesten Vaginal Tablet to Candida Strains Isolated from Clinical Vaginitis Specimens

Yan Zhen

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Abstract

OBJECTIVE To evaluate bacteriostasis of Canesten Vaginal Tablet to Candida strains in Candida Vaginitis.METHODS Minimal inhibitory concentration(MIC) of Canesten Vaginal Tablet to 100 Candida strains isolated from clinical vaginitis specimens was detected by NCCLS agar dilution method(M27-A).RESULTS MIC was 1.875~6.25mg·mL~(-1),MIC_(50),3.75mg·mL~(-1),MIC_(90),6.25mg·mL~(-1)for Candida strains;0.92~3.75mg·mL~(-1),MIC_(50),1.875mg·mL~(-1),MIC_(90)3.75mg·mL~(-1)for Candida albicans.CONCLUSION Canesten Vaginal Tablet was an inhibitory drug on all test-Candida strains in different extent,MIC of Candida albicans was the lowest.

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OBJECTIVE To evaluate bacteriostasis of Canesten Vaginal Tablet to Candida strains in Candida Vaginitis.METHODS Minimal inhibitory concentration(MIC) of Canesten Vaginal Tablet to 100 Candida strains isolated from clinical vaginitis specimens was detected by NCCLS agar dilution method(M27-A).RESULTS MIC was 1.875~6.25mg·mL~(-1),MIC_(50),3.75mg·mL~(-1),MIC_(90),6.25mg·mL~(-1)for Candida strains;0.92~3.75mg·mL~(-1),MIC_(50),1.875mg·mL~(-1),MIC_(90)3.75mg·mL~(-1)for Candida albicans.CONCLUSION Canesten Vaginal Tablet was an inhibitory drug on all test-Candida strains in different extent,MIC of Candida albicans was the lowest.

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Available abstract

OBJECTIVE To evaluate bacteriostasis of Canesten Vaginal Tablet to Candida strains in Candida Vaginitis.METHODS Minimal inhibitory concentration(MIC) of Canesten Vaginal Tablet to 100 Candida strains isolated from clinical vaginitis specimens was detected by NCCLS agar dilution method(M27-A).RESULTS MIC was 1.875~6.25mg·mL~(-1),MIC_(50),3.75mg·mL~(-1),MIC_(90),6.25mg·mL~(-1)for Candida strains;0.92~3.75mg·mL~(-1),MIC_(50),1.875mg·mL~(-1),MIC_(90)3.75mg·mL~(-1)for Candida albicans.CONCLUSION Canesten Vaginal Tablet was an inhibitory drug on all test-Candida strains in different extent,MIC of Candida albicans was the lowest.

Key concepts: Candida albicans, Vaginitis, Agar Dilution Method, Microbiology, Minimum inhibitory concentration, Agar, Agar dilution, Medicine

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