Clinical study of early diagnosis of 110 cases of neonatal infection

Objective To study the clinical significance of PCT and hs-CRP in the early diagnosis of neonatal infec tion.Methods A total of 110 neonates born in our hospital from January 2012 to January 2013 were selected and di vided into the bacteria group,the mycoplasma/chlamydia group and the virus group according to the infection pathogen and 30 healthy neonates were selected as the control group.The differences of the four groups in the clinical data were compared.Results The serum hs-CRP,PCT and WBC count of the bacteria,mycoplasma/chlamydia and virus groups increased compared to those of the healthy children group(P 0.01),of which the PCT and hs-CRP levels of the bacterial group increased most obviously.The sensitivity and specificity of the combined PCT and hs-CRP diagnosis were 29.6% and 26.9% higher than those of the combined PCT and WBC count diagnosis and 27.8% and 58.3% higher than those of the combined hs-CRP and WBC count diagnosis.Conclusion PCT,hs-CRP and WBC count can serve as the effective indicators for the diagnosis of neonatal infection and the combined hs-CRP and PCT diagnosis shows the most satisfactory specificity and sensitivity.