Liranaftate Cream in the Treatment of Tinea Cruris and Tinea Corporis:A Randomized Double-bind Vehicle-controlled Clinical Trial

Objective To study the efficacy and safety of Liranaftate cream in the topical treatment of tinea cruris and tinea corporis.Methods Clinical study was done on 144 cases of tinea cruris and tinea corporis for 4 weeks with a multiple-centre,randomized,double-bind,parallel trial.Results 138 cases have been studied.71 were in the test group,67 were in controlled group respectively.The total cure rate was 46.48% in the test group,and 40.30% in controlled group.The total efficacy rate was 83.10% in test group,and 83.58% in controlled group.The total mycological cure rate was 95.83% in test group,and 95.65% in controlled group.The side-effect rate was 0.70% in the test group,and zero in controlled group.There were no signifficant differences in clinical efficacy,mycological efficacy and side-effect between this two groups.Conclusion 2% Topical Liranaftate cream had a good efficacy and safety profile in the treatment of tinea cruris and tinea corporis.