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EFFECT OF BENZENE,TOLUENE,XYLENE OCCUPATIONAL EXPOSURE ON DNA DAMAGE IN HUMAN PERIPHERAL LYMPHOCYTE

Zhu Zhi

Open publisher page 3 citations

Abstract

Objective:To study the effect of benzene,toluene,xylene occupational exposure on DNA Damage in Human Peripheral Lymphocyte.Methods:Single cell gel electrophoresis was used.Results:There was obvious dos response relationship between the tail length,tail moment (TM), tail DNA %, ratio of moment move (RM), ratio of inertia move (RI) of comet cells and the concentration of mixed exposure to benzene,toluene,xylene.Conclusion:Mixed exposure to benzene,toluene,xylene could induce DNA damage on human peripheral lymphocyte.

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What this paper is about

Objective:To study the effect of benzene,toluene,xylene occupational exposure on DNA Damage in Human Peripheral Lymphocyte.Methods:Single cell gel electrophoresis was used.Results:There was obvious dos response relationship between the tail length,tail moment (TM), tail DNA %, ratio of moment move (RM), ratio of inertia move (RI) of comet cells and the concentration of mixed exposure to benzene,toluene,xylene.Conclusion:Mixed exposure to benzene,toluene,xylene could induce DNA damage on human peripheral lymphocyte.

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Available abstract

Objective:To study the effect of benzene,toluene,xylene occupational exposure on DNA Damage in Human Peripheral Lymphocyte.Methods:Single cell gel electrophoresis was used.Results:There was obvious dos response relationship between the tail length,tail moment (TM), tail DNA %, ratio of moment move (RM), ratio of inertia move (RI) of comet cells and the concentration of mixed exposure to benzene,toluene,xylene.Conclusion:Mixed exposure to benzene,toluene,xylene could induce DNA damage on human peripheral lymphocyte.

Key concepts: Toluene, Benzene, Xylene, Comet assay, DNA damage, Lymphocyte, Chemistry, DNA

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