2005•Chinese Journal of Critical Care MedicineRequires access

Comparison of the effects of limited fluid resuscitation and aggressive fluid resuscitation on hemorrhagic traumatic shock

Zheng Weihua

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Abstract

Objective To compare the effects of limited fluid resuscitation(LFR) and aggressive fluid resuscitation(AFR) on hemorrhagic traumatic shock in order to improve cure rate.Method To divide the patients with hemorrhagic traumatic shock into two groups: one received LFR and another received AFR;and to analyze the clinical and laboratory data.Results There were no obvious differences in the systolic blood pressure(prehospital 51±19 mmHg vs 50±21 mmHg,preoperation 74±27 mmHg vs 82±28 mmHg,P0.05),transfusion quantities were lower(prehospital 232±215 mL vs 830±542 mL,preoperation 328±309 mL vs 1905±1340 mL,P0.01),mortality rate was lower(13.3% vs 27.8%,P0.05),preoperative hemoglobin was higher(94±21 g/L vs 85±23 g/L,P0.05) and preoperative hematology indexes were better(blood platelet counts(268±94)×10~9/L vs(233±91)×10~9/L,P0.05);prothrombin time was 12.3±1.7 s vs 14.5±1.9 s,P0.01;activated partial prothrombin time was 36.5±14.1 s vs 41.8±18.5 s,P0.05 in LFR group than AFR group.Conclusion LFR for the patients with hemorrhagic traumatic shock maybe improve the outcome.

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Objective To compare the effects of limited fluid resuscitation(LFR) and aggressive fluid resuscitation(AFR) on hemorrhagic traumatic shock in order to improve cure rate.Method To divide the patients with hemorrhagic traumatic shock into two groups: one received LFR and another received AFR;and to analyze the clinical and laboratory data.Results There were no obvious differences in the systolic blood pressure(prehospital 51±19 mmHg vs 50±21 mmHg,preoperation 74±27 mmHg vs 82±28 mmHg,P0.05),transfusion quantities were lower(prehospital 232±215 mL vs 830±542 mL,preoperation 328±309 mL vs 1905±1340 mL,P0.01),mortality rate was lower(13.3% vs 27.8%,P0.05),preoperative hemoglobin was higher(94±21 g/L vs 85±23 g/L,P0.05) and preoperative hematology indexes were better(blood platelet counts(268±94)×10~9/L vs(233±91)×10~9/L,P0.05);prothrombin time was 12.3±1.7 s vs 14.5±1.9 s,P0.01;activated partial prothrombin time was 36.5±14.1 s vs 41.8±18.5 s,P0.05 in LFR group than AFR group.Conclusion LFR for the patients with hemorrhagic traumatic shock maybe improve the outcome.

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Available abstract

Objective To compare the effects of limited fluid resuscitation(LFR) and aggressive fluid resuscitation(AFR) on hemorrhagic traumatic shock in order to improve cure rate.Method To divide the patients with hemorrhagic traumatic shock into two groups: one received LFR and another received AFR;and to analyze the clinical and laboratory data.Results There were no obvious differences in the systolic blood pressure(prehospital 51±19 mmHg vs 50±21 mmHg,preoperation 74±27 mmHg vs 82±28 mmHg,P0.05),transfusion quantities were lower(prehospital 232±215 mL vs 830±542 mL,preoperation 328±309 mL vs 1905±1340 mL,P0.01),mortality rate was lower(13.3% vs 27.8%,P0.05),preoperative hemoglobin was higher(94±21 g/L vs 85±23 g/L,P0.05) and preoperative hematology indexes were better(blood platelet counts(268±94)×10~9/L vs(233±91)×10~9/L,P0.05);prothrombin time was 12.3±1.7 s vs 14.5±1.9 s,P0.01;activated partial prothrombin time was 36.5±14.1 s vs 41.8±18.5 s,P0.05 in LFR group than AFR group.Conclusion LFR for the patients with hemorrhagic traumatic shock maybe improve the outcome.

Key concepts: Medicine, Resuscitation, Hemorrhagic shock, Shock (circulatory), Prothrombin time, Anesthesia, Traumatic Shock, Blood pressure

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