Distribution and drug resistance of nonspecific infections in patients with upper urinary tract obstruction

OBJECTIVE To analyze the distribution and antibiotic resistance of the pathogens causing urinary tract infections in the patients with urinary tract obstruction so as to prevent and control urinary tract infections and provide basis for clinical application of antibiotics.METHODS The patients with urinary tract infections among the patients with upper urinary tract obstruction who were treated in department of urology from May 2009 to Nov 2011 were studied,the pathological culture for the corresponding sampling urine specimens and the drug susceptibility testing were performed.RESULTS There were totally 113 strains of pathogens isolated,including 75(66.37%) strains of gram-negative bacilli,33(29.20%) strains of gram-positive cocci and 5(4.43%) strains of fungi;there were 42 strains of Escherichia coli(37.17%),17 strains of Enterococcus(15.04%),13 strains of Staphylococcus(11.50%);multidrug-resistant bacteria were common,and the detection rate of ESBLs-producing E.coli was 47.62%.CONCLUSIONGram-negative bacilli are the main pathogens causing nonspecific infections with upper urinary tract obstruction,and Enterococcus and Staphylococcus take a large proportion;the drug resistance of the pathogens is high and some of them display multidrug-resistant;it is necessary to reasonably use antibiotics so as to reduce drug resistant strains.