The Effect of Grapefruit Juice on Clinical Drug
Ya-Fei Shang
Abstract
Ya-Fei Shang
Abstract
The consumption of grapefruit and its juice is increasing day by day in China.Because of containing many chemical compositions such as pectin,flavonoids,furocoumarin and so on,they are favored by more and more consumers.Acting on entero-transport protein and intestinal mucosa metabolic enzyme,grapefruit juice can change the bioavailability of many oral drugs.Based on the articles published in recent years about effects of grapefruit juice on oral drugs,we propose some suggestions and prospects.
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The consumption of grapefruit and its juice is increasing day by day in China.Because of containing many chemical compositions such as pectin,flavonoids,furocoumarin and so on,they are favored by more and more consumers.Acting on entero-transport protein and intestinal mucosa metabolic enzyme,grapefruit juice can change the bioavailability of many oral drugs.Based on the articles published in recent years about effects of grapefruit juice on oral drugs,we propose some suggestions and prospects.
Key concepts: Grapefruit juice, Bioavailability, Pectin, Drug, Furocoumarin, Pharmacology, Chemistry, Food science