2013•BMJRequires access

A more balanced approach to drug-grapefruit juice interactions

Warren Backman, Ameet Bakhai

Open publisher page 4 citations

Abstract

We question Pirmohamed’s focus on “severe, sometimes fatal, interactions” between grapefruit juice and drugs,1 which may bias BMJ readers and add to the excessive fear around grapefruit juice for patients and doctors alike. Grapefruit juice is a rich source of flavonoids—antioxidants that have a preventive effect in many diseases. During more than 10 years …

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What this paper is about

We question Pirmohamed’s focus on “severe, sometimes fatal, interactions” between grapefruit juice and drugs,1 which may bias BMJ readers and add to the excessive fear around grapefruit juice for patients and doctors alike. Grapefruit juice is a rich source of flavonoids—antioxidants that have a preventive effect in many diseases. During more than 10 years …

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OpenAlex reports 4 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We question Pirmohamed’s focus on “severe, sometimes fatal, interactions” between grapefruit juice and drugs,1 which may bias BMJ readers and add to the excessive fear around grapefruit juice for patients and doctors alike. Grapefruit juice is a rich source of flavonoids—antioxidants that have a preventive effect in many diseases. During more than 10 years …

Key concepts: Grapefruit juice, Fruit juice, Citrus paradisi, Drug, Food science, Medicine, Pharmacology, Psychology

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