INTRAVITREOUS INJECTION OF TRIAMCINOLONE ACETONIDE COMBINED WITH LASER THERAPY FOR MACULAR EDEMA CAUSED BY RETINAL VEIN OCCLUSION

Objective To investigate the efficacy and safety of combination of intravitreous injection of triamcinolone acetonide(TA) and laser therapy for macular edema due to retinal vein occlusion. Methods Thirty-five eyes in 35 patients,in which nine eyes in nine patients were pseudophakia,with the disease confirmed by ophthalmoscopy,optic coherent tomography and fundus fluorescein angiography were given intravitreous injection of 0.1 mL TA(40 g/L) and retinal photocoagulation.The vision,intraocular tension,lens,inflammatory reaction,fundus,thickness of retina,and vascular leakage were observed during 3-10 month follow-up. Results One and two months after therapy,the vision of all the patients improved,48.6% with a vision of 0.3-0.4,and 28.5% with a vision of ≥0.5.Compared with before treatment,the vision of 34(97%) eyes improved and one(3%) eye unimproved.Increased ocular pressure was noted in three eyes,subretinal hemorrhage in two eyes,and inflammatory cells in three eyes with pseudophakia,all occurred within 1-3 weeks after the injection.All the lens were not affected. Conclusion Combo therapy of intravitreous injection of TA plus retinal photocoagulation can effectively treat macular edema caused by retinal vein occlusion and improve patients' vision,but recurrence or increase of intraocular pressure may occur in some of them.