Effect of Omeprazole Combined with Cisapride on Reflux Esophagitis

Objective :To study the efficacy of omeprazole and cisapride in treating reflux esophagitis.Method:68 cases of digestive out-patient were diagnosed with reflux esophagitis( all by biopsy diagnosis).They were divided into two groups,36 cases in group A(observe group):20mg of omeprazole bid,5mg of cisapride tid were taken orally;32 cases in group B(control group):150mg of ranitidine bid,5mg of cisapride tid were taken orally.During the course 2,4,and 8 weeks of treatment,assess the symptom of sick,heartburn and retrosternal pain in both groups respectively,and recheck the endoscope at the end of 8 weeks.Result: The clinical curative rates were 94.4% in group A and 65.63% in group B,the efficient rates evaluation under endoscope were 90.91%,62.50% respectively.Conclusion: The efficacy of omeprazole and cisapride in treating reflux esophagitis was obviously superior to the other group.