Comparison of Transurethral Resection of Prostate and Bipolar Plasma Kinetic Resection of Prostate for Benign Prostatic Hyperplasia

Objective To compare the safety and efficacy of transurethral resection of prostate(TURP) and bipolar plasma kinetic resection of prostate(PKRP) in the treatment of benign prostatic hyperplasia(BPH). Methods Eighty BPH patients were randomly assigned to receive either TURP or PKRP under continuous epidural anesthesia. The procedures were performed using KARL STORZ resectoscope and bipolar GYRUS Plasma Kinetic System in TURP group and PKRP group, respectively.The same surgical procedures were performed in both groups: a canal reaching deep into envelope was cut to seminal colliculus at 6 o'clock position at the vesical neck. Seminal colliculus and vesical neck were the markers for excision area and the depth reached envelope as far as possible. Complete hemostasis was performed and urethral indwelling catheter was used after cutting. Then, continuous bladder flushing and anti-infective therapy were given for 3 days. The international prostate symptom score(IPSS), quality of life score(QOL), maximal urinary flow rate(Qmax), residual urine volume(RUV), operative time, bladder irrigation time, catheterization time, hospital stay and complications were compared between the two groups before and 3 and 6 months after operation. Results The intraoperative blood loss and complication rate were, respectively,(358.2±94.5) mL and 42.5% in TURP group, and(125.7±78.3) mL and 15.0% in PKRP group. There were significant differences in the two groups(P0.05). After 3-6 months of follow-up, IPSS, QOL and RUV significantly decreased but Qmax increased in both groups(P0.05). No significant differences were observed between the two groups in the same period(P 0.05). Conclusion TURP and PKRP have similar short-term efficacy in the treatment of BPH. However, PKRP is superior to TURP for reducing intraoperative blood loss and complications and enhancing safety.