Comparison of efficacy and safety between transurethral plasma kinetic resection of prostate and conventional transurethral resection of prostate for treatment of benign prostate hyperplasia

Objective To compare the efficacy and safety between transurethral plasma kinetic loop resection of prostate(PKRP) and conventional transurethral resection of prostate(TURP) for treatment of benign prostate hyperplasia(BPH).Methods Total 684 BPH patients with indication for surgery were assigned to receive PKRP or TURP according to their own will with 342 cases in each group.The International Prostate Symptom Score(EPSS),the maximum flow rate of urine(Qmax),post-void urine volume(PVR),decline in serum sodium and hemoglobin were compared before and after operation in PKRP and TURP groups.The weight of resected prostatic chips,duration of catheterization and length of hospital stay were compared between two groups.Complications of each group were also recorded after three months of operation.Results There were no significant differences in age,weight of prostate, IPSS,Qmax,PVR,hemoglobin and serum sodium before operation between TURP and PKRP groups. There were no differences in post-operation infections,urethral stricture and length of hospital stay between two groups,but the PKRP group had a less decline in hemoglobin than TURP group(7 g/L vs 17 g/L,P 0.05),a lower reduction in serum sodium levels(2 mmol/L vs 5 mmol/L,P 0.05),a shorter catheterization time(82 h vs 96 h,P 0.05).Transurethral resection syndrome(TURS) occurred in 1 case of PKRP group,but 14 cases in TURP group(P 0.05).The rate of obturator foramen reflex in PKRP group was lower than that in TURP group(1/342 vs 11/342,χ~2= 8.48,P 0.05);the rates of post-operation bleeding in PKRP group was lower than that in TURP group(5/342 vs 20/342,χ~2=9.34,P 0.05).Conclusion Compared to conventional TURP,PKRP has a similar efficacy but less complications for treatment of BPH.