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2011•Chinese Preventive MedicineRequires access

Clinical significance of serum IL-4,IL-6 and TGF-β in tuberculosis patients

LI Lei-shen

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Abstract

Objective To explore the clinical significance of serum IL-4,IL-6 and TGF-β in tuberculosis(TB) patients.Methods We selected 42 TB patients and 28 healthy controls for the study.All participants were tested for serum IL-4,IL-6 and TGF-β levels with ELISA reagents.Results The concentration of IL-4 was significantly higher in TB patients than in controls(P0.05).The concentration of serum IL-6 was higher in TB smear-positive patients than in TB smear-negative patients(P0.05).TGF-β increased significantly with the progress of treatment(P0.05).There was a positive correlation between the levels of IL-4 and TGF-β among participants.Conclusion IL-4,IL-6 and TGF-β might be useful for the prognosis of pulmonary tuberculosis.

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What this paper is about

Objective To explore the clinical significance of serum IL-4,IL-6 and TGF-β in tuberculosis(TB) patients.Methods We selected 42 TB patients and 28 healthy controls for the study.All participants were tested for serum IL-4,IL-6 and TGF-β levels with ELISA reagents.Results The concentration of IL-4 was significantly higher in TB patients than in controls(P0.05).The concentration of serum IL-6 was higher in TB smear-positive patients than in TB smear-negative patients(P0.05).TGF-β increased significantly with the progress of treatment(P0.05).There was a positive correlation between the levels of IL-4 and TGF-β among participants.Conclusion IL-4,IL-6 and TGF-β might be useful for the prognosis of pulmonary tuberculosis.

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Available abstract

Objective To explore the clinical significance of serum IL-4,IL-6 and TGF-β in tuberculosis(TB) patients.Methods We selected 42 TB patients and 28 healthy controls for the study.All participants were tested for serum IL-4,IL-6 and TGF-β levels with ELISA reagents.Results The concentration of IL-4 was significantly higher in TB patients than in controls(P0.05).The concentration of serum IL-6 was higher in TB smear-positive patients than in TB smear-negative patients(P0.05).TGF-β increased significantly with the progress of treatment(P0.05).There was a positive correlation between the levels of IL-4 and TGF-β among participants.Conclusion IL-4,IL-6 and TGF-β might be useful for the prognosis of pulmonary tuberculosis.

Key concepts: Medicine, Tuberculosis, Clinical significance, Transforming growth factor, Pulmonary tuberculosis, Internal medicine, Gastroenterology, Interleukin 10

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Clinical significance of serum IL-4,IL-6 and TGF-β in tuberculosis patients — Research Paper | ScholarLens