2013Journal of Guangdong Medical CollegeRequires access

Role of naproxen suppository and morphine epidural analgesia in post-cesarean analgesia

Xiaochun Zhang

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Abstract

Objective To observe the clinical efficacy of naproxen suppository and morphine epidural analgesia in post-cesarean pain. Methods A total of 123 pregnant women undergoing cesarean were randomly allocated to naproxen suppositoryplus morphine epidural analgesia (NM group, n=61) or morphine epidural analgesia alone (M group, n=62). VAS scores at 4 h, 8h, 12 h and 24 h, pressing times of analgesia pump within 24 h and adverse events were compared between both groups. ResultsVAS scores at all timepoints and pressing times of analgesia pump within 24 h were lower in NM group than those in M group(P0.01 or 0.05), but there was no difference in adverse events between both groups (P0.05). Conclusion Naproxensuppository plus morphine epidural analgesia is effective for post-cesarean pain and may be worthy of clinical application.

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Objective To observe the clinical efficacy of naproxen suppository and morphine epidural analgesia in post-cesarean pain. Methods A total of 123 pregnant women undergoing cesarean were randomly allocated to naproxen suppositoryplus morphine epidural analgesia (NM group, n=61) or morphine epidural analgesia alone (M group, n=62). VAS scores at 4 h, 8h, 12 h and 24 h, pressing times of analgesia pump within 24 h and adverse events were compared between both groups. ResultsVAS scores at all timepoints and pressing times of analgesia pump within 24 h were lower in NM group than those in M group(P0.01 or 0.05), but there was no difference in adverse events between both groups (P0.05). Conclusion Naproxensuppository plus morphine epidural analgesia is effective for post-cesarean pain and may be worthy of clinical application.

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Available abstract

Objective To observe the clinical efficacy of naproxen suppository and morphine epidural analgesia in post-cesarean pain. Methods A total of 123 pregnant women undergoing cesarean were randomly allocated to naproxen suppositoryplus morphine epidural analgesia (NM group, n=61) or morphine epidural analgesia alone (M group, n=62). VAS scores at 4 h, 8h, 12 h and 24 h, pressing times of analgesia pump within 24 h and adverse events were compared between both groups. ResultsVAS scores at all timepoints and pressing times of analgesia pump within 24 h were lower in NM group than those in M group(P0.01 or 0.05), but there was no difference in adverse events between both groups (P0.05). Conclusion Naproxensuppository plus morphine epidural analgesia is effective for post-cesarean pain and may be worthy of clinical application.

Key concepts: Suppository, Medicine, Morphine, Anesthesia, Adverse effect, Naproxen, Analgesic, Internal medicine

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