Application of preemptive analgesia with epidural morphine and controlled intravenous analgesia combined for patients after cesarean section

Objective To study the effect and adverse reactions of preemptive analgesia with epidural morphine and controlled intravenous analgesia combined for the patients after cesarean section.Methods Ninety patients after selective cesarean section were randomly divided into 3 groups:groupⅠ(preemptive analgesia with epidural morphine and controlled intravenous analgesia combind), groupⅡ(controlled intravenous analgesia),and GroupⅢ(controlled epidural analgesia).GroupⅠand groupⅡreceived sufentanil 100μg,metoclopramide 30 mag,and dexamethasone 10 mg in saline added to 100 ml;groupⅢreceived morphine 2 ml,0.894%ropivacaine 20 ml,metoclopramide 30 mg,and dexamethasone 10 mg in saline added to 100 ml.Sustained rate,2 ml/h;PCA single dose,0.5 ml; lockout time:15 min,analgesic time,48 h.The analgesic effect and adverse reaction were observed.Results The analgesic effects in groupⅠand groupⅢwere significantly higher than that in groupⅡ(P0.05).There were no statistically significant differences in pain score,sedation score,good analgesic rate and the rates of mild to moderate analgesia between groupⅠand groupⅡ.The incidence of urinary retention in groupⅠand groupⅢwere significantly lower than in groupⅡ(P0.01).Conclusions The preemptive analgesia with epidural morphine and controlled intravenous analgesia combined for the patients after cesarean section has safe and ideal analgesic effect with fewer adverse reactions.