The Hepatic Function Damage after Transarterial Chemoembolizations for Treating Hepatic Malignant Tumor

Objective To investigate the hepatic function damage after transarterial chemoembolizations(TACE) for treating hepatic malignant tumor.Methods Forty-two patients with hepatic malignant tumor underwent repeated TACE.The hepatic function changes of pre-operation,post-operative one day,one week,two weeks,four weeks after the first treatment and the hepatic function after repeated treatment were retrospectively reviewed.Result The median value of ALT,AST,TBIL and DBIL of post-operative one day were significantly higher than that of pre-operation(P0.001).The median value of ALT,TBIL and DBIL of post-operative one week were significantly higher than that of pre-operation(P0.001).There were no significant difference between that of post-operative two weeks,four weeks and that of pre-operation(P0.05).There were no significant difference in Child-Pugh grading after repeated TACE(P0.05).Conclusions The hepatic function damage after TACE can recover to the value of post-operative in 2-4weeks.The hepatic function should be get protection from pre-operation to post-operation.