2003•Research and Practice on Chinese MedicinesRequires access
Comparison of Buccal Sustained-release Mucoadhesive Tablets and Mucoadhesive Films
Zhou DongXin
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Abstract
Objective To compare buccal susutained-release mucoadhesive tablets and mucoadhesive films.Methods The qualities of the mucoadhesive tablets and mucoadhesive films were tested and the clinical curative effects of them were observed and compared.Results The adhesive force, dissolution, buccal adhesive test and the clinical curative effect of the tablets were better than those of the films. After absorbing water and swelling ,the tablets can be adhered to the wound of ulcer and can not be easily moved. The tablets can make the curative effects as well as protect the wound and the curative effects can be longer.Conclusion The function of the susutained-release mucoadhesive tablets is better than that of films. The curative effect is remarkable. However, the preparation of tablets is complex and the preparation of films is simple.