Correlation Among Triglyceride and Coagulative and Fibrinolytic Parameters in Patients with Coronary Heart Disease

【Objective】To investigate the correlation among serum triglyceride concentration,plasma factor Ⅶ clouting(FⅦc),tPA,PAI-I activity in 73 cases with coronary heart disease(CHD).【Methods】One hundred and fifty three cases were divided into four groups: 73 patients with CHD were divided into two groups based on serum triglyceride concentration.40 subjects with high triglyceride without CHD;another 40 subjects with normal triglyceride.The results in 73 patients with CHD and 40 subjects with high triglyceride were compared with those in 40 normal triglyceride.Serum triglyceride was measured by enzyme method.The plasma PA1-I,tPA activity were measured by spectrophotometry,the plasma FⅦc by one stage method.【Results】FⅦc and PAI-I activity in patients with CHD and in high serum triglyceride group were higher than those in normal triglyceride group.FⅦc and PAI-I activity in high triglyceride patients with CHD were significantly higher than those in high triglyceride cases without CHD.【Conclusion】Serum high triglyceride concentration is associatied with FⅦc,tPA and PAI-I.