Risk factors and treatment methods of intracranial infection after craniotomy

Objective To investigate the risk factors and treatment methods of intracranial infection after craniotomy.Methods Of the 1446 patients who underwent craniotomy, 48 patients were complicated by intracranial infection. Data of the 48 patients were analysed retrospectively.Results Many risk factors were associated with intracranial infection after craniotomy. There were significant differences in elective operation, operation on other part of the body and general anesthesia between the two groups (P0.05).Conclusion Emergent operation, operation at posterior cranial fossa and basal anesthesia are risk factors of postoperative intracranial infection. Strict aseptic technique, minimally invasive surgery,use of effective antibiotics in periopertive period and corresponding preventive measures can reduce the incidence of intracranial infection after surgery. Using correct antibiotics in the treatment of intracranial infection can improve the therapeutic results.