ScholarLens Back to search
2008•Huaxi yaoxue zazhiRequires access

Structure modification of mangiferin

Qiang Yang

Open publisher page 4 citations

Abstract

OBJECTIVE In order to look for new antidiabetic compounds,the structure of mangiferin is modified.METHODS Using mangiferin as starting material,a series of 3,6,7-O-trisubstituted derivatives of mangiferin were synthesized,and then their antidiabetic activities were tested in vitro with mangiferin as the control.RESULTS A total of 11 target compounds were synthesized,and their structures were all confirmed by 1HNMR.CONCLUSION Compounds 5 and 11 were shown to have better antidiabetic activities than mangiferin.

About this research paper

What this paper is about

OBJECTIVE In order to look for new antidiabetic compounds,the structure of mangiferin is modified.METHODS Using mangiferin as starting material,a series of 3,6,7-O-trisubstituted derivatives of mangiferin were synthesized,and then their antidiabetic activities were tested in vitro with mangiferin as the control.RESULTS A total of 11 target compounds were synthesized,and their structures were all confirmed by 1HNMR.CONCLUSION Compounds 5 and 11 were shown to have better antidiabetic activities than mangiferin.

Why it matters

OpenAlex reports 4 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE In order to look for new antidiabetic compounds,the structure of mangiferin is modified.METHODS Using mangiferin as starting material,a series of 3,6,7-O-trisubstituted derivatives of mangiferin were synthesized,and then their antidiabetic activities were tested in vitro with mangiferin as the control.RESULTS A total of 11 target compounds were synthesized,and their structures were all confirmed by 1HNMR.CONCLUSION Compounds 5 and 11 were shown to have better antidiabetic activities than mangiferin.

Key concepts: Mangiferin, Chemistry, Organic chemistry, Stereochemistry, Chromatography

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Structure modification of mangiferin — Research Paper | ScholarLens