High-dose urokinase via minimally invasive approach for the treatment of 90 cases of ventricular hemorrhage

Objective To analyze the clinical effect of high-dose urokinase via minimally invasive approach for the treatment of ventricular hemorrhage.Methods A total of 90 cases of ventricular hemorrhage were divided into control group and treatment group randomly.Lateral ventricular injection of urokinase after external ventricular drainage plus drainage of lumbar cistern were performed in control group,and lateral ventricular injection of urokinase after external ventricular drainage plus drainage of lumbar cistern with injection of urokinase were performed in treatment group.Results In treatment group,the time of lumbar cistern drainage was 6 d in average,and the time of ventricular hematoma elimination was(5±1.47) d.In control group,the average time of lumbar cistern drainage was 12 d and the time of ventricular hematoma elimination was(11±3.76) d.Conclusion Compared with control group,ventricular injection of urokinase after external ventricular drainage plus lumbar cistern injection of urokinase are helpful for the hematoma elimination and increase of survival rate.