To Explore the Screening Algorithm for Non-remunerate Voluntary Blood Donations

Objective To assess the effect of different blood screening algorithms on the screening results,to stipulate for a proper blood screening policy under the guidance of the new version of Blood Bank Technique Regulations of China.Methods Blood screening results of 37 136 non-remunerate voluntary blood donations from Shanghai Fengxian Blood Bank in 2010 to 2011 were selected,among which 13 693 were pre-donated blood samples from appointment blood donors,10 398 were donation samples from appointment blood donors,and 13 054 were donation samples from un-appointment blood donors.2 705 donation samples from un-appointment donors with ALT pre-screened were also been selected.The blood screening results were analyzed to enclose the effect of different screening algorithms.Results Abnormal ALT were the main unqualified reasons both in appointment and in un-appointment blood donations.The unqualified rate of appointment donations(2.70%) was significant lower than that of un-appointment donations(5.62%).ALT screening before blood donation could significantly decrease the unqualified rate(from 6.33% to 2.88%).And the unqualified rate of HBsAg or anti-HCV also could be significantly decreased in appointment donations(0.73%) when compared to un-appointment donations(1.85%).Conclusion For the non-remunerate voluntary blood donor,the best screening policy would be appointment donation,which had qualified HBsAg,anti-HCV and other viral markers in appointment testing,and ALT screening before donation.