Distribution and resistance of pathogentic bacteria in blood culture.

Objective To investigate the distribution and drug resistance of pathogenic bacteria in blood culture in order to provide references for clinical antimicrobial drug usage reasonably. Method Blood samples from blood department in our hospital were cultured and used to detect the bacteria and drug sensitivity tests,then the results were analyzed statistically.Result The 239 strains of bacteria were isolated from samples of blood culture,131 strains(52.6%) gram-negative microbes and 99 strains(39.8%) gram-positive microbes and 9 strain(6.8%) fungi were among 239 strains.The positive rates of ESBLs in Escherichia coli and in K.pneumoniae were respectively 54.2%and 48.6%.They were only highly sensitive to imipenem,tazocin and amikacin and the sensitivity rates were over 85%.Among the G+ c,the positive rates of MRSA and MRCNS were 42.9% and 89.2% respectively,and the pathogens were only sensitive to vancomycin and the sensitivity rates were reached 100%.But enterococci showed highly multiple drug resistance already.Conclusion The distribution of pathogenic bacteria in blood culture is complicated,and the positive rates of ESBLs and MRS are high.So the test results of blood culture should be seriously in clinical and are of great significance directing clinical chemotherapy.