Clinical Effect of Combination Therapy on Paraquat Poisoning Patients

Objective To investigate the clinical effect of combination therapy on paraquat poisoning patients.Methods Forty cases of paraquat poisoning were divided into two groups.Control group was given gastric lavage and catharsis,protection stomach mucous membrane,dehydration,diuretics,corticosteroids,and mechanical ventilation treatment.On the basis of the conventional treatment,combination therapy group was treated with Smecta,Medicinal Charcoal Tablets or slime water,diarrhea by mannitol,poison elimination by hemoperfusion,methylprednisolone and cyclophosphamide to prevent the lung fibrosis,oxyradical elimination by Xuebijing and edaravone.The transformation on patients' condition was observed.Results In the control group,the efficiency rate was 31.25%.And in the combination therapy group,the efficiency rate was 75.0%,there was significant difference between the two groups(χ2 =7.52,P0.01).Conclusion Combination therapy was much better than conventional treatment in paraquat poisoning.