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2006•Shanghai Journal of Traditional Chinese MedicineRequires access

Effects of Serum Containing "Tongbi Decoction" on in Vitro Articular Chondrocyte Generation and Levels of MMP-3 and TIMP-1 in Rabbits

Wei Ji

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Abstract

Objective To investigate the effects of serum containing Tongbi on in vitro articular chondrocyte generation and the levels of MMP-3 and TIMP-1. Methods The serum was added to culture medium of rabbit articular chondrocyte and the generation of chondrocyte was detected, and the levels of MMP-3 and TIMP-1 was determined. Results The serum could upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1. Conclusion The Decoction can upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1 .

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What this paper is about

Objective To investigate the effects of serum containing Tongbi on in vitro articular chondrocyte generation and the levels of MMP-3 and TIMP-1. Methods The serum was added to culture medium of rabbit articular chondrocyte and the generation of chondrocyte was detected, and the levels of MMP-3 and TIMP-1 was determined. Results The serum could upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1. Conclusion The Decoction can upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1 .

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Available abstract

Objective To investigate the effects of serum containing Tongbi on in vitro articular chondrocyte generation and the levels of MMP-3 and TIMP-1. Methods The serum was added to culture medium of rabbit articular chondrocyte and the generation of chondrocyte was detected, and the levels of MMP-3 and TIMP-1 was determined. Results The serum could upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1. Conclusion The Decoction can upgrade chondrocyte proliferation and degrade MMP-3/TIMP-1 .

Key concepts: Chondrocyte, Decoction, Medicine, Matrix metalloproteinase, In vitro, Andrology, Articular cartilage, Pharmacology

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Effects of Serum Containing "Tongbi Decoction" on in Vitro Articular Chondrocyte Generation and Levels of MMP-3 and TIMP-1 in Rabbits — Research Paper | ScholarLens